Structural classification and properties of ketoacyl reductases, hydroxyacyl dehydratases and enoyl reductases

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Structural classification and properties of ketoacyl reductases, hydroxyacyl dehydratases and enoyl reductases.

Ketoacyl reductases (KRs), hydroxyacyl dehydratases (HDs) and enoyl reductases (ERs) are part of the fatty acid and polyketide synthesis cycles. Their reverse reactions, catalyzed by acyl dehydrogenases (equivalent to ERs), enoyl hydratases (equivalent to HDs) and hydroxyacyl dehydrogenases (equivalent to KRs), are part of fatty acid degradation by β-oxidation. These enzymes have been classifie...

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ژورنال

عنوان ژورنال: Protein Engineering Design and Selection

سال: 2012

ISSN: 1741-0126,1741-0134

DOI: 10.1093/protein/gzs050